On a coastal route in the South of Europe, three compartments of a train hold groups of strangers.

In one, a stressed out British couple with a screaming baby find themselves seated next to a wild Roma woman. In the next, a Middle Eastern man having a quarter-life crisis sits with a European woman having a mid-life crisis. He speaks Assyrian and she speaks German. In the last, a deaf brother and sister have to find a way to help an Asian backpacker who is on the wrong train...

En Route explores human connection and non-verbal communication – the catalytic moments that turn strangers into friends.